Apheresis
What is apheresis (component blood collection)?
This method involves temporarily circulating blood outside the body to efficiently collect only the target cells.
It is used to collect immune cells and their precursor cells, which are difficult to obtain in sufficient quantities through general blood sampling, and plays an important role in immunotherapy.
It uses a mechanism similar to hemodialysis, but only the necessary cells from the blood are collected, and the other blood components are returned to the body.
Mechanism of apheresis
Blood is circulated outside the body to isolate and collect the target cells, while the remaining blood components are returned to the body.
Why is apheresis (component blood sampling) necessary?
In immunotherapy, the patient's own immune cells are collected, cultured and activated outside the body, and then returned to the body.
Depending on the type and quantity of cells required for treatment, a standard blood test may not be sufficient to obtain a adequate number of cells.
By performing apheresis (component blood collection), it becomes possible to efficiently collect the necessary cells, leading to higher quality cell culture and treatment.
Apheresis (component blood sampling) at our hospital
Component blood sampling is performed using a specialized component separation device.
Blood is drawn from a vein in the arm, the target cells are separated and collected in a device, and the remaining blood components are returned to the body.
During treatment, doctors and medical staff will monitor blood pressure, pulse, and other vital signs to ensure safety.
The time required varies depending on the type and amount of cells to be collected, but it generally takes about 3 to 5 hours.
After the sample collection is complete, you will be asked to rest for a certain period of time, and once we have confirmed that you are in good health, you may go home.
Regarding safety
Component blood sampling is an established medical technique that has been performed in medical settings for many years.
Serious complications are rare, but the following symptoms may occur:
● Pain at the puncture site, subcutaneous bleeding
● Temporary drop in blood pressure or discomfort
● Numbness in the lips, hands, and feet
● Dizziness
● Fatigue
Many of these issues are temporary and will improve with appropriate action.
If you experience any concerning symptoms during treatment, please inform the medical staff immediately.